Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Ser144 (L-E-SP-L-R)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; cas9; CASP 9; CASP9; caspase 9, apoptosis-related cysteine peptidase; Caspase-9 subunit p10; Caspase-9 subunit p35; Caspase9; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; protein phosphatase 1, regulatory subunit 56
APAF-3; APAF3; CASP9; ICE-LAP6; MCH6; PPP1R56