|Western Blot (WB)||0.1-0.5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 18-31 of human caveolin 2, phosphorylated on serine 23.|
|Purification||Antigen affinity chromatography|
|Storage buffer||1% BSA, 50% glycerol|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-25625 detects Caveolin 2 (phospho S23) from human samples.
PA1-25625 has been successfully used in Western blot procedures.
The PA1-25625 immunogen is a synthetic peptide corresponding to residues 18-31 of human caveolin 2, phosphorylated on serine 23.
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAV; caveolae protein, 20-kD; caveolin 2 isoform a and b; Caveolin-2; MGC12294
Gene Aliases: CAV; CAV2
UniProt ID: (Human) P51636
Entrez Gene ID: (Human) 858
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.