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|Tested species reactivity||Rat, Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human CDK5 around the phosphorylation site of Tyrosine 15|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Cdk5 is expressed in both cycling and noncycling cells and is present in numerous mammalian tissues. Neuronal and muscle cells contain the highest amount of this protein. The p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CDK5; cell division protein kinase 5; CR6 protein kinase; CRK6; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; EC 22.214.171.124; kinase Cdk5; protein kinase CDK5 splicing; PSSALRE; serine/threonine-protein kinase PSSALRE; TAU protein kinase II catalytic subunit; TPKII catalytic subunit
AW048668; Crk6; PSSALRE