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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of threonine 286 (A-C-T(p)-P-T) derived from Human Cyclin D1.|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for Western blot is MCF-7 cells.
Cyclin D1 (Bcl-1 oncogene product), is a member of the Cyclin family that help control transition between phases of the cell cycle by acting as regulatory subunits of the Cdks. The D-type Cyclins are composed of three subtypes, Cyclin D1, D2 and D3. Cyclin D1 is essential for control of the cell cycle at the G1/S transitions and interacts with Cdk4 or Cdk6 protein kinases. On the recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Also Cyclin D1 involves in development and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL-1 oncogene; BCL1; CCND1; CYL-1; G1/S-specific cyclin D1; G1/S-specific cyclin-D1; PRAD1; PRAD1 oncogene
AI327039; bcl-1; BCL1; CCND1; cD1; CycD1; Cyl-1; D11S287E; PRAD1; U21B31