This antibody detects endogenous protein at a molecular weight of 48 kDa.
Purity is >95% by SDS-PAGE.
Cyclins were first identified in invertebrates as proteins that oscillate dramatically through the cell cycle. These proteins have been well conserved through evolution and play a critical role in regulation of cell division. cyclin E, along with the three cyclin D proteins and cyclin C, has been shown to represent a putative G1 cyclin on the basis of its cyclic pattern of mRNA expression, with maximal levels being detected near the G1/S boundary. cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCNE; CCNE1; cyclin E; G1/S-specific cyclin-E1
Gene Aliases: AW538188; CCNE; CCNE1; CycE1; CYCLE; pCCNE1