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Product Details
PA5-36750
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic phosphopeptide derived from human ERF around the phosphorylation site of Threonine 526 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2553702 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 59 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 [PubMed 9192842]). For further information on ETS transcription factors, see ETS1 (MIM 164720).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Est2 repressor factor; ETS domain-containing transcription factor ERF; Ets2 repressor factor; PE-2
Gene Aliases: CRS4; ERF; PE-2; PE2
UniProt ID: (Human) P50548, (Mouse) P70459
Entrez Gene ID: (Human) 2077, (Rat) 292721, (Mouse) 13875
Molecular Function:
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
cell cycle
cell differentiation
in utero embryonic development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
ectodermal cell differentiation
trophoblast giant cell differentiation
chorio-allantoic fusion
regulation of transcription, DNA-templated
Performance Guarantee
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