|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of tyrosine 588/596 (K-T-Y(p)-V-R)/(R-T-Y(p)-V-D) derived from Human EPHA2/3/4.|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for Western blot is HepG2 cells; suggested positive control for ICC/IF is Hela cells.
These proteins belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
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Protein Aliases: ARCC2; CTPA; CTPP1; ECK; EK4; EK8; EPH-like kinase 4; EPH-like kinase 8; Eph-like tyrosine kinase 1; Ephrin type-A receptor 2; Ephrin type-A receptor 3; Ephrin type-A receptor 4; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; ETK1; HEK; HEK4; HEK8; Human embryo kinase; human embryo kinase 1; receptor protein-tyrosine kinase HEK8; SEK; soluble EPHA2 variant 1; testicular tissue protein Li 64; TYRO1; TYRO1 protein tyrosine kinase; TYRO4; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor MPK-5; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase receptor SEK-2; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase TYRO4
Gene Aliases: 2900005C20Rik; AI385584; ARCC2; AW492086; AW545284; Cek4; Cek8; CTPA; CTPP1; CTRCT6; ECK; EK4; End3; EPHA2; EPHA3; EPHA4; ETK; ETK1; HEK; HEK4; HEK8; Mek4; Myk2; rb; SEK; Sek-2; Sek1; Sek2; TYRO1; TYRO4
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