|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phosphopeptide derived from human EphA3 around the phosphorylation site of Tyrosine 602|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 110 and 135 kDa.
Purity is >95% by SDS-PAGE.
The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EK4; EPH-like kinase 4; Eph-like tyrosine kinase 1; EPHA3; Ephrin type-A receptor 3; ETK1; HEK; hEK4; Human embryo kinase; human embryo kinase 1; rEK4; testicular tissue protein Li 64; TYRO4; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ETK1; tyrosine-protein kinase receptor REK4; Tyrosine-protein kinase TYRO4
Gene Aliases: AW492086; Cek4; EK4; End3; EPHA3; ETK; ETK1; HEK; HEK4; Mek4; Rek4; TYRO4
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.