This antibody is predicted to react with mouse and rat based on sequence homology.
receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3.
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Protein Aliases: Developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; EK6; ELK; ELK-related tyrosine kinase; EPH tyrosine kinase 2; EPH tyrosine kinase 3; EPH-like kinase 5; EPH-like kinase 6; EPHB1; EPHB2; EphB2/CTF1; EphB2/CTF2; Ephrin type-B receptor 1; Ephrin type-B receptor 2; EPHT2; EPHT3; EPTH3; ERK; HEK6; NET; Neuronally-expressed EPH-related tyrosine kinase; protein-tyrosine kinase HEK5; Renal carcinoma antigen NY-REN-47; soluble EPHB1 variant 1; Tyrosine-protein kinase receptor EPH-2; Tyrosine-protein kinase receptor EPH-3; Tyrosine-protein kinase TYRO5
Gene Aliases: CAPB; DRT; EK5; ELK; EPHB1; EPHB2; EPHT2; EPHT3; EPTH3; ERK; HEK5; HEK6; NET; PCBC; TYRO5