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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human Ephrin B1/B2 around the phosphorylation site of Tyr329 (P-V-YP-I-V)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CAPB; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPHB2, Ephrin type-B receptor 1; EPHB3, DRT; ephrin-B1; ephrin-B2; EPHT3; ERK; ETK2; HEK2; Hek5; HTK ligand; LERK-2; LERK-5; ligand of eph-related kinase 5; MGC87492; NET, HEK-6, ELK, Ephrin type-B receptor 2, Ephrin B1, EphrinB1, Ephrin B2, EphrinB2; PCBC; Tyro5; TYRO6
Cek5-L; CFND; CFNS; EFB1; EFL-3; EFL3; EFNB1; EFNB2; ELF-2; Elf2; Elk-L; Epl2; Epl5; EPLG2; EPLG5; Htk-L; HTKL; LERK-2; LERK-5; LERK2; LERK5; NLERK-1; Stra1