|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human EPHB1/2 around the phosphorylation site of Tyr594/604 (K-I-YP-I-D)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase family. The protein encoded by this gene is a receptor for ephrin-B family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAPB; Developmentally-regulated Eph-related tyrosine kinase; EK5; EK6; ELK; ELK, NET, Hek6, EPHT2, FLJ37986, EPHB1, DRT; ELK-related protein tyrosine kinase; ELK-related tyrosine kinase; Eph receptor B2 (ELK-related protein tyrosine kinase); EPH tyrosine kinase 2; EPH tyrosine kinase 3; EPH-like kinase 5; EPH-like kinase 6; EPHB2, Ephrin type-B receptor 2, Ephrin type-B receptor 1, EphrinB2, Ephrin B2, EphrinB1, Ephrin B1; Ephrin type-B receptor 1; Ephrin type-B receptor 2; EPHT3; ERK; Hek5; MGC87492; NET; Neural kinase; Neuronally-expressed EPH-related tyrosine kinase; Nuk receptor tyrosine kinase; PCBC; protein-tyrosine kinase HEK5; Renal carcinoma antigen NY-REN-47; soluble EPHB1 variant 1; Tyro5; Tyrosine-protein kinase receptor EPH-2; Tyrosine-protein kinase receptor EPH-3; Tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase TYRO5
Gene Aliases: 9330129L11; AW488255; C130099E04Rik; CAPB; Cek5; Cek6; DRT; EK5; ELK; Elkh; ENSMUSG00000074119; EPHB1; EPHB2; EPHT2; EPHT3; Epth2; EPTH3; ERK; ETECK; HEK5; HEK6; NET; Nuk; PCBC; Prkm5; Qek5; RGD1564232; Sek3; TYRO5
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