A suggested positive control for Western blot is K562 cells; suggested positive control for IHC is human brain tissue.
Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
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Protein Aliases: EFL-3; EFL6; EFNB2; EFNB3; ELK ligand; ELK-L; EPH related receptor transmembrane ligand ELK L3; EPH related receptor tyrosine kinase ligand 8; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; Ephrin B3; Ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B2; Ephrin-B3; EPLG5; EPLG8; HTK ligand; HTK-L; HTKL; LERK-2; LERK-5; LERK-8; LERK5; LERK8; ligand of eph-related kinase 5
Gene Aliases: CFND; CFNS; EFB1; EFL3; EFL6; EFNB1; EFNB2; EFNB3; Elk-L; EPLG2; EPLG5; EPLG8; Htk-L; HTKL; LERK2; LERK5; LERK8