|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Miscellaneous PubMed (MISC)||See 3 publications below|
|Western Blot (WB)||See 10 publications below|
|Immunohistochemistry - Free Floating (IHC (Free))||See 1 publications below|
|Species reactivity||Human, Mouse, Rat|
|Published species||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human GSK-3a/b that contains tyrosine 279/216. The sequence is conserved in rat and zebrafish GSK-3a and mouse, rat, frog and zebrafish GSK-3b.|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.3, with 1mg/ml BSA, 50% glycerol|
|Contains||0.05% sodium azide|
Glycogen synthase kinase-3 beta (GSK3 beta) belongs to the subfamily of glycogen synthase kinases, that play a central role in energy metabolism, neuronal cell development, and body pattern formation. GSK3 has alpha and beta isoforms (51 kDa and 47 kDa respectively), that are functionally dissimilar. GSK3 beta plays a role in insulin and Wnt signaling, and is inhibited following the extracellular signaling events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 220.127.116.11; FA; Factor A; Glycogen Synthase Kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK-3 beta Factor A; GSK3B; GSK3beta isoform; Serine/threonine-protein kinase GSK3B
Gene Aliases: 7330414F15Rik; 8430431H08Rik; C86142; GSK-3; GSK-3beta; GSK3; GSK3B
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