Glycogen synthase kinase-3 beta (GSK3 beta) belongs to the subfamily of glycogen synthase kinases, that play a central role in energy metabolism, neuronal cell development, and body pattern formation. GSK3 has alpha and beta isoforms (51 kDa and 47 kDa respectively), that are functionally dissimilar. GSK3 beta plays a role in insulin and Wnt signaling, and is inhibited following the extracellular signaling events.
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Protein Aliases: EC 220.127.116.11; FA; Factor A; Glycogen Synthase Kinase 3 beta; glycogen synthase kinase-3 beta; GSK-3 beta; GSK-3 beta Factor A; GSK3B; GSK3beta isoform; serine/threonine-protein kinase GSK3B
Gene Aliases: 7330414F15Rik; 8430431H08Rik; C86142; GSK-3; GSK-3beta; GSK3