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7TM Antibodies
Phospho-Galanin Receptor 1 (Thr340) Polyclonal Antibody
FIGURE: 1 / 1
Phospho-Galanin Receptor 1 (Thr340) Antibody (7TM0243A) in WB
Agonist-induced Threonine340 phosphorylation of GAL1 Receptor. Upper panel, HEK293 cells stably expressing the GAL1-Receptor (GAL1) were either not exposed or exposed to 1 µM of specific GAL-Receptor Agonist Galanin for 30 minutes. Cells were lysed and immunoblotted with the anti-pT340-GAL1 antibody (7TM0243A) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with the phosphorylation-ind... View More
Product Details
7TM0243A
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human GAL1 around the phosphorylation site Thr340.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gal receptor 1; Gal-1 receptor; Gal-r1; GAL1-R; Galanin r1 receptor; Galanin receptor type 1; Galanin-1 receptor; Galn1r; GALR-1; Hugal 1-r
Gene Aliases: GALNR; GALNR1; GALR1
UniProt ID: (Human) P47211
Entrez Gene ID: (Human) 2587
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
digestion
positive regulation of transcription from RNA polymerase II promoter
positive regulation of cortisol secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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