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      View (13) other GluR1 antibodies

      Invitrogen

      Phospho-GluR1 (Ser845) Polyclonal Antibody

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      Catalog #:36-8300

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      Product Details

      TESTED APPLICATIONS DILUTION
      ELISA (ELISA) Assay Dependent
      Immunofluorescence (IF) Assay Dependent
      Immunohistochemistry (IHC) 1:1000
      Western Blot (WB) 1:1000
      PUBLISHED APPLICATIONS
      Western Blot (WB) See 2 publications below
      Immunohistochemistry - Free Floating (IHC (Free)) See 1 publications below
      Tested Species reactivity Rat
      Published species reactivity Mouse
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Synthetic phospho-peptide derived from the rat GluR1 protein.
      Conjugate Unconjugated
      Form Liquid
      Purification Antigen affinity chromatography
      Storage buffer 0.01M HEPES, pH 7.5, with 100µg/ml BSA, 50% glycerol, 0.15M NaCl
      Contains no preservative
      Storage conditions -20°C
      RRID AB_2533280

      Background/Target Information

      The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct subunits GluR1-4 and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is also potentiated by phosphorylation at Ser831. In addition, phosphorylation of this site has been linked to synaptic plasticity as well and learning and memory.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References (3)

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      Bioinformatics

      Protein Aliases: AMPA 1; AMPA-selective glutamate receptor 1; GluA1; GLUH1; GluR-1; GluR-A; GluR-K1; GLUR1; GLURA; glutamate receptor; Glutamate receptor 1; glutamate receptor A; Glutamate receptor ionotropic; Glutamate receptor ionotropic, AMPA 1; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA1 (alpha 1); GRIA1; HBGR1; ionotropic; MGC133252

      Gene Aliases: GluA1; gluR-A; Glur1; Gria1

      UniProt ID: (Rat) P19490

      Entrez Gene ID: (Rat) 50592

      Molecular Function: ion channel ionotropic glutamate receptor ligand-gated ion channel receptor transporter

      Suggested Secondary Antibodies

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      Material safety data sheets (MSDS)

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