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Phospho-GluR4 (Ser862) Antibody (PA5-36807) in WB
Western blot analysis of Phospho-GluR4 (Ser862) in Lane 1: HEK293T whole cell lysate (40 µg), Lane 2: U-87MG whole cell lysate (40 µg), Lane 3: A2780 whole cell lysate (40 µg), Lane 4: C6 whole cell lysate (40 µg), Lane 5: BV2 whole cell lysate (40 µg). Samples were incubated with Phospho-GluR4 (Ser862) polyclonal antibody (Product # PA5-36807) at a dilution of 1:500.
Product Details
PA5-36807
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide derived from human GluR4 around the phosphorylation site of Serine 862
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2553746
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 100 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AMPA-selective glutamate receptor 4; GluA4; GluR-4; GluR-D; glutamate receptor; Glutamate receptor 4; glutamate receptor channel alpha 4; Glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); spike wave 1
Gene Aliases: GluA4; Glur-4; GluR-D; GLUR4; GLUR4C; Gluralpha4; GLURD; GRIA4; spkw1
UniProt ID: (Human) P48058, (Mouse) Q9Z2W8, (Rat) P19493
Entrez Gene ID: (Human) 2893, (Mouse) 14802, (Rat) 29629
transport
glutamate receptor signaling pathway
chemical synaptic transmission
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
response to fungicide
ion transport
synaptic transmission, glutamatergic
modulation of synaptic transmission
positive regulation of synaptic transmission, glutamatergic
regulation of synapse structure or activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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