Immunogen sequence: NESPW; Positive Samples: HeLa; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, Nucleus
Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocorticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.
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Protein Aliases: glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene Aliases: GCCR; GCR; GCRST; GR; GRL; NR3C1
UniProt ID: (Human) F5ATB7
Entrez Gene ID: (Human) 2908