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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human HCK around the phosphorylation site of Tyr410 (N-E-YP-T-A)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
HCK is a member of the Srcfamily of tyrosine kinases. This protein is primarily hemopoietic,particularly in cells of the myeloid and B-lymphoid lineages. Itmay help couple the Fc receptor to the activation of therespiratory burst. In addition, it may play a role in neutrophilmigration and in the degranulation of neutrophils. Multipleisoforms with different subcellular distributions are produced dueto both alternative splicing and the use of alternative translationinitiation codons, including a non-AUG (CUG) codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B cell/myeloid kinase; B-cell/myeloid kinase; hematopoietic cell kinase; hemopoietic cell kinase; hemopoietic cell tyrosine kinase; JTK9; p56-HCK; p56-HCK/p59-HCK; p59-HCK/p60-HCK; tyrosine-protein kinase HCK
AI849071; Bmk; HCK; Hctk; JTK9; p56Hck; p59Hck; p61Hck