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Invitrogen
Phospho-HCLS1 (Tyr397) Recombinant Rabbit Monoclonal Antibody (HS1Y397-F12), APC
FIGURE: 1 / 1
Phospho-HCLS1 (Tyr397) Antibody (MA5-37162) in Flow
Flow cytometry of Phospho-HS1 (Tyr397) using Ramos cells. Samples were incubated in monoclonal Phospho-HS1 (Tyr397) antibody (Product # MA5-37162). Images correspond with the following conditions: untreated, unstained negative control (blue), untreated (red), treated with pervanadate (green).
Product Details
MA5-37162
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HS1Y397-F12
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human phospho HS1.
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.20% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897096
Target Information
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell-specific protein; LckBP1; p75
Gene Aliases: AW213261; CTTNL; HCLS1; HS1; lckBP1; p75
UniProt ID: (Human) P14317, (Mouse) P49710
Entrez Gene ID: (Human) 3059, (Mouse) 15163
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
positive regulation of cell proliferation
response to hormone
positive regulation of phosphatidylinositol 3-kinase signaling
actin filament polymerization
erythrocyte differentiation
regulation of actin filament polymerization
positive regulation of granulocyte differentiation
positive regulation of peptidyl-serine phosphorylation
intracellular signal transduction
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of transcription factor import into nucleus
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of protein kinase B signaling
cellular response to cytokine stimulus
negative regulation of leukocyte apoptotic process
positive regulation of actin cytoskeleton reorganization
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