This antibody is predicted to react with bovine, chicken, guinea pig, non-human primate, rat and sheep based on 100% sequence homology.
This antibody contains enough material to conduct 10 mini-Western blots.
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD2; Histone deacetylase 2; transcriptional regulator homolog RPD3; YY1 transcription factor-binding protein; YY1-associated factor 1; Yy1bp
Gene Aliases: D10Wsu179e; HD2; HDAC2; mRPD3; RPD3; YAF1; Yy1bp