Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
sequential chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol, 150mM NaCl |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2816508 |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ16239; HD6; HDA6; histone deacetylase 5; Histone deacetylase 6; Histone deacetylase mHDA2; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Tubulin-lysine deacetylase HDAC6
Gene Aliases: CPBHM; HD6; Hdac5; HDAC6; JM21; KIAA0901; mHDA2; PPP1R90; Sfc6
UniProt ID: (Human) Q9UBN7, (Mouse) Q9Z2V5
Entrez Gene ID: (Human) 10013, (Mouse) 15185
Molecular Function:
chromatin/chromatin-binding, or -regulatory protein
histone modifying enzyme
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