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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phosphopeptide corresponding to the amino acids around Ser 165 conjugated to KLH|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34978 targets Phospho-HEC1 pSer165 in ICC, IF, and WB applications and shows reactivity with Human, Mouse, and Rat samples.
The PA5-34978 immunogen is synthetic phosphopeptide corresponding to the amino acids around Ser 165 conjugated to KLH.
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
HEC; HEC1; highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80 homolog, kinetochore complex component; NDC80 kinetochore complex component homolog; retinoblastoma-associated protein HEC; TID3
2610020P18Rik; AV139730; HEC; HEC1; HsHec1; hsNDC80; KNTC2; NDC80; TID3