The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.
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Protein Aliases: high mobility group nucleosomal binding domain 2; High mobility group nucleosome-binding domain-containing protein 2; high mobility group protein 17; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; high-mobility group nucleosome-binding domain-containing protein 2; Non-histone chromosomal protein HMG-17; nonhistone chromosomal protein HMG-17
Gene Aliases: HMG-17; HMG17; HMGN2