|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human ICK around the phosphorylation site of Tyr159(T-D-YP-V-S)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ICK is a 632 amino acid protein, belonging to the CMGC Ser/Thr protein kinase family, containing a single protein kinase domain. It is an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. It localizes to the intestinal crypt region and plays important role in intestinal epithelial cell proliferation and differentiation and is also needed for cardiac development. ICK is expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine, colon and in many cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.