This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 59 kDa serine/threonine-protein kinase; epididymis secretory protein Li 28; ILK-1; ILK-2; ILK1; ILK2; integrin-linked kinase; integrin-linked kinase-2; Integrin-linked protein kinase; p59ILK
Gene Aliases: HEL-S-28; ILK; ILK-1; ILK-2; ILK1; ILK2; P59; p59ILK
UniProt ID: (Human) Q13418
Entrez Gene ID: (Human) 3611