|
Mouse
|
Not Cited
|
Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.
44-804G was used in western blot to investigate the effects of nicotinamide adenine dinucleotide phosphate reduced oxidase 4 in liver tissues from patients with NASH and mice with steatohepatitis.
|
Bettaieb A,Jiang JX,Sasaki Y,Chao TI,Kiss Z,Chen X,Tian J,Katsuyama M,Yabe-Nishimura C,Xi Y,Szyndralewiez C,Schröder K,Shah A,Brandes RP,Haj FG,Török NJ
|
Gastroenterology
(149:468)
|
2015
|
|
Not Applicable
|
1:5000
|
The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.
44-804G was used in western blot to study the structures of the insulin receptor and the insulin-like growth factor-1 receptor
|
Cabail MZ,Li S,Lemmon E,Bowen ME,Hubbard SR,Miller WT
|
Nature communications
(6:null)
|
2015
|
|
Not Applicable
|
Not Cited
|
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21.
44-804G was used in western blot to examine the ability of methionine restriction to reverse age-induced obesity and insulin resistance in adult mice
|
Lees EK,Król E,Grant L,Shearer K,Wyse C,Moncur E,Bykowska AS,Mody N,Gettys TW,Delibegovic M
|
Aging cell
(13:817)
|
2014
|
|
Mouse
|
Not Cited
|
Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity.
44-804G was used in western blot to study the protective effects against cardiac steatosis and dilated cardiomyopathy of specifically overexpressing triglyceride lipase in cardiomyocytes in a murine model of diet-induced obesity.
|
Pulinilkunnil T,Kienesberger PC,Nagendran J,Sharma N,Young ME,Dyck JR
|
International journal of obesity (2005)
(38:205)
|
2014
|
|
Human
|
Not Cited
|
Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes.
44-804G was used in western blot to identify direct and indirect EBF targets in fat.
|
Griffin MJ,Zhou Y,Kang S,Zhang X,Mikkelsen TS,Rosen ED
|
The Journal of biological chemistry
(288:35925)
|
2013
|
|
Mouse
|
1.25 ug/m
|
Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus.
44-804G was used in western blot to test if alterations in retinoic acid-responsive genes contribute to the beneficial effects of fenretinide on obesity and insulin resistance.
|
Mcilroy GD,Delibegovic M,Owen C,Stoney PN,Shearer KD,McCaffery PJ,Mody N
|
Diabetes
(62:825)
|
2013
|
|
Rat
|
1:1000
|
Calorie restriction enhances insulin-stimulated glucose uptake and Akt phosphorylation in both fast-twitch and slow-twitch skeletal muscle of 24-month-old rats.
44-804G was used in western blot to examine the insulin signaling pathway in isolated epitrochlearis and soleus muscles of old rats.
|
Sequea DA,Sharma N,Arias EB,Cartee GD
|
The journals of gerontology. Series A, Biological sciences and medical sciences
(67:1279)
|
2012
|
|
Mouse
|
Not Cited
|
Reducing amyloid-related Alzheimer's disease pathogenesis by a small molecule targeting filamin A.
|
Wang HY,Bakshi K,Frankfurt M,Stucky A,Goberdhan M,Shah SM,Burns LH
|
The Journal of neuroscience : the official journal of the Society for Neuroscience
(32:9773)
|
2012
|
|
Human
|
Not Cited
|
Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.
|
Haque A,Andersen JN,Salmeen A,Barford D,Tonks NK
|
Cell
(147:185)
|
2011
|
|
Not Applicable
|
Not Cited
|
Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B.
44-804G was used in western blot to elucidate mechanisms of protein-tyrosine phosphatase degradation
|
Trümpler A,Schlott B,Herrlich P,Greer PA,Böhmer FD
|
The FEBS journal
(276:5622)
|
2009
|
|
Not Applicable
|
1:500
|
BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells.
44-804G was used in western blot to test a new insulin-like growth factor receptor tyrosine kinase inhibitor using MCF10A cells and human breast cancer cell lines
|
Litzenburger BC,Kim HJ,Kuiatse I,Carboni JM,Attar RM,Gottardis MM,Fairchild CR,Lee AV
|
Clinical cancer research : an official journal of the American Association for Cancer Research
(15:226)
|
2009
|
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