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Antibody detects endogenous levels of JunB only when phosphorylated at Serine 259.
JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB
Gene Aliases: AP-1; Jun-b; JUNB
UniProt ID: (Human) P17275, (Rat) P24898, (Mouse) P09450
Entrez Gene ID: (Human) 3726, (Rat) 24517, (Mouse) 16477
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