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Bioss
Phospho-LLGL1/LLGL2 (Ser650, Ser654) Polyclonal Antibody
Product Details
BS-6070R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DLG4; HGL; Hugl-1; human giant larvae homolog; Human homolog to the D-lgl gene protein; lethal giant larvae homolog 1; lethal giant larvae homolog 1, scribble cell polarity complex component; lethal giant larvae homolog 2; lethal giant larvae homolog 2, scribble cell polarity complex component; Lethal giant larvae-like protein 2; Lethal(2) giant larvae protein homolog 1; Lethal(2) giant larvae protein homolog 2; LLGL; LLGL scribble cell polarity complex component 2; Mgl-1; Mlgl
Gene Aliases: 9130006H11Rik; AI325176; DLG4; HGL; HUGL; HUGL-1; Hugl-2; HUGL1; Lgl1; LGL2; LLGL; LLGL1; LLGL2; Llglh; Llglh2; Mgl1; RGD1560307; Rgl-1; Rgl1
UniProt ID: (Human) Q15334, (Human) Q6P1M3, (Mouse) Q80Y17, (Mouse) Q3TJ91
Entrez Gene ID: (Human) 3996, (Human) 3993, (Rat) 54265, (Mouse) 16897, (Rat) 360661, (Mouse) 217325
protein complex assembly
exocytosis
Golgi to plasma membrane transport
axonogenesis
regulation of Notch signaling pathway
regulation of exocytosis
neurogenesis
cortical actin cytoskeleton organization
regulation of establishment or maintenance of cell polarity
positive regulation of GTPase activity
regulation of protein secretion
establishment of spindle orientation
cell division
maintenance of apical/basal cell polarity
brain development
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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