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7TM Antibodies
Phospho-Lysophosphatidic Acid Receptor 4 (Thr336, Thr338) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-Lysophosphatidic Acid Receptor 4 (Thr336, Thr338) Antibody (7TM0094A) in WB
Agonist-induced Threonine336/Threonine338 phosphorylation of the Lysophosphatidic Acid Receptor 4. Upper panel, HEK293 cells stably expressing the LPA4-Receptor (LPA4) were either not exposed or exposed to 1 µM of LPA4-Receptor agonists 1-oleoyl-LPA for 30 minutes. Cells were lysed and immunoblotted with the anti-pT336/pT338-LPA4 antibody (7TM0094A) at a dilution of 1:1,000. Lower panel, blot was stripped a... View More
Product Details
7TM0094A
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human LPA4 around the phosphorylation site of Thr336/Thr338.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor 23; G-protein-coupled receptor; LPA receptor 4; LPA-4; LPA4 Receptor; Lysophosphatidic acid receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; P2Y9; Purinergic receptor 9; unnamed protein product
Gene Aliases: GPR23; LPA4; LPAR4; P2RY9; P2Y5-LIKE; P2Y9
UniProt ID: (Human) Q99677
Entrez Gene ID: (Human) 2846
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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