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|Tested species reactivity||Human|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Dot blot (DB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with mouse and rabbit based on sequence homology.
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development.
PA5-12619 was used in western blot to explore the regulatory functions of the BMP and Wnt pathways in early tooth development.
|Yuan G,Yang G,Zheng Y,Zhu X,Chen Z,Zhang Z,Chen Y||Development (Cambridge, England) (142:128)||2015|
MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAPK-2; MAPKAPK2
MAPKAP-K2; MAPKAPK2; MK-2; MK2