This antibody is predicted to react with mouse and rat based on sequence homology.
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MADS box transcription enhancer factor 2, polypeptide D; MEF2D; Myocyte-specific enhancer factor 2D
Gene Aliases: MEF2D
UniProt ID: (Human) Q14814
Entrez Gene ID: (Human) 4209