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7TM Antibodies
Phospho-Melanin-Concentrating Hormone Receptor 1 (Thr348, Ser350) Polyclonal Antibody
FIGURE: 1 / 1
Phospho-Melanin-Concentrating Hormone Receptor 1 (Thr348, Ser350) Antibody (7TM0280B) in WB
Agonist-induced Threonine348/Serine350 phosphorylation of MCH1 Receptor. Upper panel, HEK293 cells stably expressing the MCH1-Receptor (MCH1) were either not exposed or exposed to 1 µM of MCH1-Receptor Agonist MCH for 30 minutes. Cells were lysed and immunoblotted with the anti-pT348/pS350-MCH1 antibody (7TM0280B) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an phosphorylation-... View More
Product Details
7TM0280B
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human MCH1 around the phosphorylation site Thr348/Ser350.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor 24; G-protein coupled receptor 24; GPCR24; MCH 1 receptor; MCH receptor 1; MCH-1R; MCH1; MCH1R; Melanin-concentrating hormone receptor 1; SLC-1; Somatostatin receptor-like protein
Gene Aliases: GPR24; MCH-1R; MCH1R; MCHR1; SLC-1; SLC1
UniProt ID: (Human) Q99705
Entrez Gene ID: (Human) 2847
generation of precursor metabolites and energy
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
feeding behavior
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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