Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human Myd88 around the phosphorylation site of Tyr257. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
sequential chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol, 150mM NaCl |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2817586 |
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: mutant myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; Myeloid differentiation primary response protein MyD88
Gene Aliases: MYD88; MYD88D
UniProt ID: (Human) Q99836, (Rat) Q6Y1S1, (Mouse) P22366
Entrez Gene ID: (Human) 4615, (Rat) 301059, (Mouse) 17874
Molecular Function:
scaffold/adaptor protein
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