Phospho-NDRG1 (Thr346) Polyclonal Antibody detects endogenous levels of NDRG1 only when phosphorylated at Thr346.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAP43; Differentiation-related gene 1 protein; DRG-1; DRG1; N-myc downstream regulated 1; N-myc downstream regulated gene 1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Protein Ndr1; Protein NDRG1; protein regulated by oxygen-1; Reducing agents and tunicamycin-responsive protein; Rit42; RTP
Gene Aliases: CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NDRG1; Ndrl; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5