NHE3 (also known as SLC9A3 - Sodium/hydrogen exchanger 3) is a member of the sodium/hydrogen exchanger family that plays a crucial role in acid-base and volume homeostasis by mediating the majority of sodium and bicarbonate reabsorption in the proximal tubule of the kidney. Mutations in the gene can lead to Diarrhea 8.
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Protein Aliases: MGC126718; MGC126720; Na(+)/H(+) exchanger 3; NHE-3; NHE-3 antibody; plasma membrane ion transport protein; SLC9A3 antibody; Sodium/hydrogen exchanger 3; Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter 3, Na+/H+ (amiloride insensitive); solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; solute carrier family 9 (sodium/hydrogen exchanger), member 3; Solute carrier family 9 member 3; solute carrier family 9, member 3; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Gene Aliases: NHE3; SLC9A3