Product References
Schweinfurthin induces ICD without ER stress and caspase activation.
Oncoimmunology
Zhang R,Neighbors JD,Schell TD,Hohl RJ
MA5-15033 was used in Western Blotting to investigate the mechanisms by which MeSG treatment induces immunogenic cell death (ICD).
Tue Aug 09 00:00:00 EDT 2022
Swimming Differentially Affects T2DM-Induced Skeletal Muscle ER Stress and Mitochondrial Dysfunction Related to MAM.
Diabetes, metabolic syndrome and obesity : targets and therapy
Zhang Z,Cui D,Zhang T,Sun Y,Ding S
MA5-15033 was used in Western Blotting to show that MAM quality and ATF6 might be novel and important targets for T2DM treatment.
Thu Apr 14 00:00:00 EDT 2022
Spata7 is required for maintenance of the retinal connecting cilium.
Scientific reports
Lu J,Xiong K,Qian X,Choi J,Shim YK,Burnett J,Mardon G,Chen R
MA5-15033 was used in Immunohistochemistry to indicate that Spata7 is required not only for the establishment but also for the maintenance of the CC of photoreceptors.
Sat Apr 02 00:00:00 EDT 2022
Four-dimensional nuclear speckle phase separation dynamics regulate proteostasis.
Science advances
Dion W,Ballance H,Lee J,Pan Y,Irfan S,Edwards C,Sun M,Zhang J,Zhang X,Liu S,Zhu B
MA5-15033 was used in Western Blot to show an evolutionarily conserved XBP1s-SON axis that establishes a cell-autonomous mammalian 12-hour ultradian rhythm of nuclear speckle liquid-liquid phase separation dynamics, separate from both the 24-hour circadian clock and the cell cycle.
Fri Jan 07 00:00:00 EST 2022
Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection.
PLoS neglected tropical diseases
Weingartner M,Stücheli S,Jebbawi F,Gottstein B,Beldi G,Lundström-Stadelmann B,Wang J,Odermatt A
MA5-15033 was used in Western Blot to study the involvement of unfolded protein response and endoplasmic reticulum-stress during E. multilocularis infection in mice.
Sat Jan 01 00:00:00 EST 2022
Leptin Induces Apoptotic and Pyroptotic Cell Death via NLRP3 Inflammasome Activation in Rat Hepatocytes.
International journal of molecular sciences
Baral A,Park PH
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Mon Nov 22 00:00:00 EST 2021
Leptin Induces Apoptotic and Pyroptotic Cell Death via NLRP3 Inflammasome Activation in Rat Hepatocytes.
International journal of molecular sciences
Baral A,Park PH
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Mon Nov 22 00:00:00 EST 2021
Schizandrin A induces the apoptosis and suppresses the proliferation, invasion and migration of gastric cancer cells by activating endoplasmic reticulum stress.
Molecular medicine reports
Pu H,Qian Q,Wang F,Gong M,Ge X
MA5-15033 was used in Western Blotting to identify how schizandrin A functioned to affect the progression of gastric cancer.
Mon Nov 01 00:00:00 EDT 2021
Inhibition of eIF2α Dephosphorylation Protects Hepatocytes from Apoptosis by Alleviating ER Stress in Acute Liver Injury.
BioMed research international
Tang YJ,Chen H,Yi Y,Chen GM,Yang FW,Li Y,Tian RD,Huang WG,Cheng QJ,He YH
MA5-15033 was used in Western Blotting to investigate the effects of eIF2α phosphorylation on hepatocyte apoptosis and the ER stress mechanisms in acute liver injury.
Mon Mar 22 00:00:00 EDT 2021
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
BMC cancer
Du R,Sullivan DK,Azizian NG,Liu Y,Li Y
MA5-15033 was used in Western Blotting to reveal a critical role for ERAD in therapeutic response of FTS and points to the modulation of UPR as a novel approach to improve the efficacy of FTS in PDAC treatment.
Sat Mar 06 00:00:00 EST 2021
Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons.
EBioMedicine
Arioka Y,Shishido E,Kushima I,Suzuki T,Saito R,Aiba A,Mori D,Ozaki N
MA5-15033 was used in Western Blotting to conclude that the 22q11.2 deletion causes various vulnerabilities in dopaminergic neurons, dependent on PERK dysfunction.
Fri Jan 01 00:00:00 EST 2021
Inhibition of USP14 induces ER stress-mediated autophagy without apoptosis in lung cancer cell line A549.
Cell stress & chaperones
Moghadami AA,Aboutalebi Vand Beilankouhi E,Kalantary-Charvadeh A,Hamzavi M,Mosayyebi B,Sedghi H,Ghorbani Haghjo A,Nazari Soltan Ahmad S
MA5-15033 was used in Western Blotting to determine whether the accumulation of ubiquitinated proteins results in endoplasmic reticulum stress-mediated autophagy.
Sun Nov 01 00:00:00 EDT 2020
Inhibition of TGFβ-activated protein kinase 1 ameliorates myocardial ischaemia/reperfusion injury via endoplasmic reticulum stress suppression.
Journal of cellular and molecular medicine
Zeng J,Jin Q,Ruan Y,Sun C,Xu G,Chu M,Ji K,Wu L,Li L
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Mon Jun 01 00:00:00 EDT 2020
Inhibition of TGFβ-activated protein kinase 1 ameliorates myocardial ischaemia/reperfusion injury via endoplasmic reticulum stress suppression.
Journal of cellular and molecular medicine
Zeng J,Jin Q,Ruan Y,Sun C,Xu G,Chu M,Ji K,Wu L,Li L
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Mon Jun 01 00:00:00 EDT 2020
Antifungal itraconazole ameliorates experimental autoimmune encephalomyelitis through a novel mechanism of action.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Huang H,Tian X,Peng X,Huang L,Mei L,Zhan Y,Chen S,Wu H,Wei G,Cai X
MA5-15033 was used in Western Blotting to reveal a new method for treating MS using currently approved antifungal drugs.
Fri May 01 00:00:00 EDT 2020
Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells.
Translational neurodegeneration
Sun H,Jiang M,Fu X,Cai Q,Zhang J,Yin Y,Guo J,Yu L,Jiang Y,Liu Y,Feng L,Nie Z,Fang J,Jin L
MA5-15033 was used in Western Blotting to study the role of HSP70 expression in the mesencephalic astrocyte-derived neurotrophic factor (MANF) - mediated survival pathway.
Wed Nov 20 00:00:00 EST 2019
Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury.
Cell death & disease
Kim HJ,Joe Y,Rah SY,Kim SK,Park SU,Park J,Kim J,Ryu J,Cho GJ,Surh YJ,Ryter SW,Kim UH,Chung HT
MA5-15033 was used in Western Blotting to demonstrate that the activation of protein kinase R-like endoplasmic reticulum kinase with carbon monoxide increases the nuclear translocation of transcription factor EB.
Wed Oct 17 00:00:00 EDT 2018
HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response.
Scientific reports
Chusri P,Kumthip K,Hong J,Zhu C,Duan X,Jilg N,Fusco DN,Brisac C,Schaefer EA,Cai D,Peng LF,Maneekarn N,Lin W,Chung RT
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Tue Mar 01 00:00:00 EST 2016
Protein tyrosine phosphatase receptor R and Z1 expression as independent prognostic indicators in oral squamous cell carcinoma.
Head & neck
Duś-Szachniewicz K,Woźniak M,Nelke K,Gamian E,Gerber H,Ziółkowski P
MA5-15033 was used in western blot to study the function of PTPRR and PTPRZ1 proteins in oral cavity squamous cell carcinoma
Tue Dec 01 00:00:00 EST 2015
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Nature communications
Treacy-Abarca S,Mukherjee S
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Wed Jul 29 00:00:00 EDT 2015
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Nature communications
Treacy-Abarca S,Mukherjee S
Published figure using Phospho-PERK (Thr980) monoclonal antibody (Product # MA5-15033) in Western Blot
Wed Jul 29 00:00:00 EDT 2015