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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phosphopeptide corresponding to a portion of of human Progesterone Receptor containing serine 294.|
|Storage buffer||HEPES buffered saline with 100µg/ml BSA, 50% glycerol|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Dot blot (DB)||1:1000-1:2000|
|Western Blot (WB)||1:1000-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-25647 detects Progesterone Receptor (phospho S294) from human samples.
PA1-25647 has been successfully used in Western blot and dot blot procedures.
The PA1-25647 immunogen is a synthetic phosphopeptide corresponding to a portion of of human Progesterone Receptor containing serine 294.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
NR3C3; nuclear receptor subfamily 3 group C member 3; PGR
NR3C3; PGR; PR