Invitrogen

Phospho-RGS19 (Ser24) Polyclonal Antibody

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Phospho-RGS19 (Ser24) Antibody in Dot blot (DB) — Dot blot analysis of Phospho-RGS19 pSer24 polyclonal antibody (Product # PA5-12826) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg per mL.

Product Details

Tested Applications

Dilution

Dot blot (DB)

1:500

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S24 of human RGS19

Conjugate

Unconjugated

Form

Liquid

Concentration

Lot-specific

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2178055

Target Information

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; G-alpha-interacting protein; GAIP; GAIP protein; GAIP, GNAI3IP; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19

Gene Aliases: GAIP; GNAI3IP; RGS19; RGSGAIP

UniProt ID: (Human) P49795

Entrez Gene ID: (Human) 10287

Molecular Function: G-protein modulator enzyme modulator