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|Tested species reactivity||Mouse, Rat, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human Smad1 around the phosphorylation site of Serine 465|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BSP-1; BSP1; dwarfin-A; Dwf-A; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; Mad-related protein 1; Mad1; MADH1; MADR1; mMad1; Mothers against decapentaplegic homolog 1; Mothers against DPP homolog 1; mothers-against-DPP-related 1; Mothers-against-DPP-related-1; SMAD 1; SMAD, mothers against DPP homolog 1; TGF-beta signaling protein 1; Transforming growth factor- beta signaling protein-1; transforming growth factor-beta signaling protein 1; transforming growth factor-beta-signaling protein 1
AI528653; BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1; Mlp1; MusMLP
Nucleoside, nucleotide and nucleic acid metabolism mRNA transcription mRNA transcription regulation Signal transduction Cell surface receptor mediated signal transduction Receptor protein serine/threonine kinase signaling pathway Intracellular signaling cascade Other intracellular signaling cascade Cell communication Ligand-mediated signaling Oncogenesis Developmental processes