Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. SFR is required for cardiac differentiation and maturation.
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Protein Aliases: C-FOS SERUM RESPONSE ELEMENT-BINDING FACTOR; c-fos serum response element-binding transcription factor; minichromosome maintenance 1 homolog; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); SRF
Gene Aliases: AW049942; AW240594; MCM1; RGD1559787; SRF