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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human Catenin-alpha1 around the phosphorylation site of Ser641 (D-D-SP-D-F)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
a-catenins are a group of proteins associated with cadherin cell-cell adhesion molecules and play indispensable roles in the function of the cadherins. a N-catenin is a linker between cadherin adhesion receptors and the Actin cytoskeleton and is essential for stabilizing dendritic spines in rodent hippocampal neurons in culture. A deletion in this protein causes cerebellar and hippocampal lamination defects and impaired startle reaction. a E- and a N-catenin appear to co-localize in cell bodies of neurons in dorsal root ganglia. In mice, a N-catenin was found to occur at the roof plate of the mesencephalon and diencephalon, coinciding with Wnt-1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
102 kDa cadherin-associated protein; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; alphaE-catenin; alphaN-catenin; cadherin associated protein; CAP102; CAPR; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha-1; Catenin alpha1; Catenin alpha2; Catenin-alpha1; Catenin-alpha2; CTNNA1; CTNNA2; renal carcinoma antigen NY-REN-13
2010010M04Rik; AA517462; AI988031; CAP102; Catna1; CTNNA1; MDPT2