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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||HEp-2 cells expressing Placental Alkaline Phosphatase (PLAP)|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ELISA (ELISA)||See 1 publications below|
MA5-12691 targets Placental Alk Phosphatase in ELISA and IHC applications and shows reactivity with Human samples.
The MA5-12691 immunogen is hEp-2 cells expressing Placental Alkaline Phosphatase (PLAP).
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A vast repertoire of Dscam binding specificities arises from modular interactions of variable Ig domains.
MA5-12691 was used in ELISA to study the wide range of Dscam binding specificities arising from modular interactions of variable Ig domains
|Wojtowicz WM,Wu W,Andre I,Qian B,Baker D,Zipursky SL||Cell (130:1134)||2007|
alkaline phosphatase; alkaline phosphatase Regan isozyme; alkaline phosphomonoesterase; glycerophosphatase; placental alkaline phosphatase 1; placental type; PLAP-1; Regan isozyme
ALP; ALPP; PALP; PLAP; PLAP-1