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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein encoding human Placental Alkaline Phosphatase (PLAP)|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 3 publications below|
MA5-14544 targets Placental Alk Phosphatase in IHC (P) applications and shows reactivity with Human samples.
The MA5-14544 immunogen is recombinant protein encoding human Placental Alkaline Phosphatase (PLAP).
Reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. This antibody is highly specific to PLAP and shows no cross-reaction with other isoenzymes of alkaline phosphatases. It is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Pulmonary histiocytic sarcoma mimicking pulmonary Langerhans cell histiocytosis in a young adult presenting with spontaneous pneumothorax: a potential diagnostic pitfall.
MA5-14544 was used in immunohistochemistry to report on a case of pulmonary histiocytic sarcoma mimicking pulmonary Langerhans cell histiocytosis
|Stacher E,Beham-Schmid C,Terpe HJ,Simiantonaki N,Popper HH||Virchows Archiv : an international journal of pathology (455:187)||2009|
Dedifferentiated Liposarcoma of the Retroperitoneum with Extensive Leiomyosarcomatous Differentiation and beta-Human Chorionic Gonadotropin Production.
MA5-14544 was used in immunohistochemistry to report a clinical case of dedifferentiated liposarcoma of the retroperitoneum with unique features
|Russell MJ,Flynt FL,Harroff AL,Fadare O||Sarcoma (2008:null)||2008|
Association of intratubular seminoma and intratubular embryonal carcinoma with invasive testicular germ cell tumors.
MA5-14544 was used in immunohistochemistry to examine the pathogenesis of nonseminomatous germ cell tumors
|Lau SK,Weiss LM,Chu PG||The American journal of surgical pathology (31:1045)||2007|
alkaline phosphatase; alkaline phosphatase Regan isozyme; alkaline phosphomonoesterase; glycerophosphatase; placental alkaline phosphatase 1; placental type; PLAP-1; Regan isozyme
ALP; ALPP; PALP; PLAP; PLAP-1