|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||The N-terminal region of human plakophilin-1.|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:250|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-2004 contains 200 ug of in vitro produced, protein A purified antibody (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide.
MA1-2004 detects plakophilin-1from human samples.
MA1-2004 has been successfully used in Western blot applications. By Western blot, MA1-2004 detects a ~70 kDa band representing plakophilin-1 from MCF-7 cells.
The MA1-2004 immunogen is the N-terminal region of human plakophilin-1.
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.