|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Human Factor IV purified from the supernatant of thrombin activated platelets.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17641 targets Platelet Factor 4 in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17641 immunogen is human Factor IV purified from the supernatant of thrombin activated platelets.
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; CXCL4; Iroplact; Oncostatin-A; PF-4; Platelet factor 4; SCYB4
Gene Aliases: CXCL4; PF-4; PF4; SCYB4
UniProt ID: (Human) P02776
Entrez Gene ID: (Human) 5196
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.