|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Human Factor IV purified from the supernatant of thrombin activated platelets.|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17640 targets Platelet Factor 4 in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17640 immunogen is human Factor IV purified from the supernatant of thrombin activated platelets.
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.