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Plexin-A1 Antibody (MA5-31857) in ELISA
ELISA analysis of PLXNA1 in Control Antigen (black line, 100 ng); Antigen (purple line, 10 ng); Antigen (blue line, 50 ng); Antigen (red line, 100 ng). Samples were incubated with PLXNA1 monoclonal antibody (Product # MA5-31857) using a dilution of 1:10,000.
Product Details
MA5-31857
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
7B8H9
Immunogen
Purified recombinant fragment of human PLXNA1 (AA: 1100-1200) expressed in E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787480
Product Specific Information
MA5-31857 has been tested in indirect ELISA.
Target Information
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plexin 1; Plexin-A1; Semaphorin receptor NOV
Gene Aliases: NOV; NOVP; PLEXIN-A1; PLXN1; PLXNA1
UniProt ID: (Human) Q9UIW2
Entrez Gene ID: (Human) 5361
multicellular organism development
regulation of smooth muscle cell migration
branchiomotor neuron axon guidance
regulation of cell migration
regulation of axon extension involved in axon guidance
dichotomous subdivision of terminal units involved in salivary gland branching
semaphorin-plexin signaling pathway involved in axon guidance
neuron projection extension
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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