FIGURE: 1 / 5
MA5-31856 has been tested in indirect ELISA.
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: plexin 1; Plexin-A1; Semaphorin receptor NOV
Gene Aliases: NOV; NOVP; PLEXIN-A1; PLXN1; PLXNA1
UniProt ID: (Human) Q9UIW2
Entrez Gene ID: (Human) 5361