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Invitrogen
Plexin-A1 Recombinant Rabbit Monoclonal Antibody (JU50-37)
Product Details
MA5-32804
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JU50-37
Immunogen
Recombinant protein within Human Plexin A1 aa 100-200
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2810080
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plex 1; plexin 1; plexin A1; plexin-1; Plexin-A1; Semaphorin receptor NOV
Gene Aliases: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; PlexA1; PLEXIN-A1; PLXN1; PLXNA1; RGD1560871
UniProt ID: (Human) Q9UIW2, (Mouse) P70206
Entrez Gene ID: (Human) 5361, (Rat) 362398, (Mouse) 18844
multicellular organism development
regulation of smooth muscle cell migration
branchiomotor neuron axon guidance
regulation of cell migration
regulation of axon extension involved in axon guidance
dichotomous subdivision of terminal units involved in salivary gland branching
semaphorin-plexin signaling pathway involved in axon guidance
neuron projection extension
semaphorin-plexin signaling pathway
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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