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Alomone Labs, LTD
Plexin-A1 (extracellular) Polyclonal Antibody, FITC
FIGURE: 1 / 2
Plexin-A1 (extracellular) Antibody (APR-081-F-50UL) in Flow
Cell surface detection of PLXNA1 in live intact human THP-1 monocytic leukemia cells: - (black line) cells. (red) Cells + Rabbit IgG isotype control-FITC. (green) Cells + Anti-Plexin-A1 (extracellular)-FITC Antibody (APR-081-F), (2.5 µg Antibody /0.5x106cells).
Product Details
APR-081-F-50UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)REVAPITRGQGDQR, corresponding to amino acid residues 623-636 of human PLXNA1, Extracellular, N-terminus
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plex 1; plexin 1; plexin A1; plexin-1; Plexin-A1; Semaphorin receptor NOV
Gene Aliases: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; PlexA1; PLEXIN-A1; PLXN1; PLXNA1; RGD1560871
UniProt ID: (Human) Q9UIW2, (Mouse) P70206
Entrez Gene ID: (Human) 5361, (Rat) 362398, (Mouse) 18844
multicellular organism development
regulation of smooth muscle cell migration
branchiomotor neuron axon guidance
regulation of cell migration
regulation of axon extension involved in axon guidance
dichotomous subdivision of terminal units involved in salivary gland branching
semaphorin-plexin signaling pathway involved in axon guidance
neuron projection extension
semaphorin-plexin signaling pathway
signal transduction
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